New York, Global Protein A Resin Market was valued at USD 1.2 billion in 2021 and it is anticipated to grow up to USD 3.0 billion by 2031, at a CAGR of 9.6% during the forecast period.
The global protein A resin market report from Global Insight Services is the single authoritative source of intelligence on Protein A Resin Market. The report will provide you with analysis of impact of latest market disruptions such as Russia-Ukraine war and Covid-19 on the market. Report provides qualitative analysis of the market using various frameworks such as Porters’ and PESTLE analysis. Report includes in-depth segmentation and market size data by categories, product types, applications, and geographies. Report also includes comprehensive analysis of key issues, trends and drivers, restraints and challenges, competitive landscape, as well as recent events such as M&A activities in the market.
Protein A resins are the most frequently used affinity resins in biomanufacturing. Protein A chromatography is a very efficient purification procedure and is used as a capture step due to its specificity. Depending on the intended use for the target molecule (antibodies for diagnostic testing) Protein A capturing could be the sole chromatographic step required to achieve adequate product purity.
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Market Trends and Drivers
Ongoing surge in antibody engineering worldwide will propel protein A resins market growth. Growing investment in synthetic biology and increasing focus on drug development by biotechnology and pharmaceutical companies will propel the industry growth. Biopharmaceutical industry are extensively using protein engineered products in their research activities to develop broad range of protein-based drugs. Therefore, rising use of chromatography in drug discovery and research industry will propel the market growth over the forecasted time period. Increasing demand of monoclonal antibodies (mAb) globally for the better treatment of chronic diseases and increasing number of pharmaceutical and biotechnology companies will boost the overall protein A resins industry growth. With better treatment options with the help of immunotherapy, the adoption will also surge. However, high cost associated with product may hinder market opportunities during the analysis timeframe.
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Global Protein A Resin Market Segmental Overview
The report analyses the global protein A resin market based on product, application matrix type, end use, and region.
Global Protein A Resin Market by Product
Based on product, it is segmented into natural protein A and recombinant protein A. Recombinant protein A resins market for significant CAGR during the forecast period. Recombinant proteins are used to prepare nanoparticles for protein drug carrier. Thus, with expanding innovation in drug discovery, the market demand will increase through 2026. Recombinant protein A is mainly used to improve solubility and to normalise sensitivity of alkaline solutions. With expanding pharmaceuticals industry and increasing technological advancements in novel drug development, the segment will proceed at significant rate.
Global Protein A Resin Market by Application
Based on application, segmented into immunoprecipitation and antibody purification. The antibody purification segment dominated the global market and accounted for the largest share in 2021. Antibody purification includes specific isolation and specific enrichment of antibodies from polyclonal antibodies, ascites fluid and cell culture supernatant of monoclonal antibodies. Rising demand for monoclonal antibodies has triggered the commercial production and purification of mAb using protein A resins.
Global Protein A Resin Market by Matrix Type
Based on matrix type, it is segmented into agarose-based matrix, glass or silica gel-based matrix and organic polymer-based matrix. Agarose-based matrix type accounted for largest revenue size in 2021. It is gaining massive popularity and will continue to show growth due to wide use in pharmaceutical and biotechnology industry. Owing to its high gelling strength at low concentrations, anti-convection medium for gel electrophoresis, suitable pH range and superior mechanical strength, this segment will witness positive growth.
Global Protein A Resin Market by End-use
Based on end-use, it is segmented into biopharmaceutical companies, clinical research laboratories, academic research institutes and contract research organizations. The biopharmaceutical companies segment dominated the market in 2021. Due to rising prevalence of various chronic diseases and increasing demand of better treatment methods, biopharmaceutical industry will foresee high demand for protein A resins. Increasing demand for protein engineering with various advancements will further boost segmental growth. Growing application in chromatography in biopharmaceutical industry will also provide substantial segment growth.
Geographical Analysis of Global Protein A Resin Market
Region-wise, it is studied across North America, Europe, Asia Pacific, and the Rest of the World. North America is the largest regional market in protein A resin market. Regional growth is mainly attributed to presence of major market players constantly investing into research and development activities. Furthermore, rising prevalence of autoimmune and orphan diseases and increasing demand of better treatment methods will boost the regional market growth in the region. Presence of major industry players in the U.S. and increasing incidence of chronic diseases will favor the U.S. protein A resins market growth. Moreover, growing demand of technologically advanced products in this country will highly impact the market growth. Furthermore, increasing drug delivery and development will offer positive market growth in the country.
Major Players in the Global Protein A Resin Market
The key players in the market are GE Healthcare (US), Merck Millipore (Germany), Repligen Corporation (US), Thermo Fisher Scientific (US), Tosoh Bioscience (Japan), Purolite Corporation (US), Novasep Holding SAS (France), Agilent Technologies (US), GenScript Biotech Corporation (China), and PerkinElmer (US) among others.
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